TheMASI scores in both groups decreased over time, with only the TXA group improving significantly, especially in patients with severe melasma. Both groups saw an increase in MASI scores after stopping treatment between weeks 12 and 24, but the scores did not return to baseline. The same trend occurred with the melanin index scores. TheMASI score was calculated and color photographs were taken of all patients under standard conditions in natural light. In a prepeel program, patients were Of the 20 cases of melasma which were treated with GA, there was 79% reduction in epidermal melasma (from mean MASI of 25.5 to 5.6) and 48% reduction in mixed melasma cases (from Melasmaseverity was assessed by the MASI and subjective evaluation (2 studies with the mean MASI score, 7 studies with the mMASI score, 8 studies with the subjective evaluation). Three therapeutic regimens were used for PRP treatment: microinjection (1 study), microneedling (2 studies), intradermal injection (8 studies). Inour study, patients treated with 82% lactic acid showed reduction in posttreatment MASI score when compared with baseline. Mean MASI score after 12 weeks of treatment was 1.865 while that at baseline was 2.885 representing a decrease of 1.02 and a % improvement of 35.36% at 12 weeks. In follow-up period the MASI score decreased Theretrospective study of data from 79 patients with melasma stratifies the mMASI score into ranges (mild, moderate, and severe) to correlate with melasma Thescore of each item on the MELASQoL scale was determined using a random-effects model. Results: Fourteen studies with a total of 1398 melasma patients were included in the systematic review, four of which were eligible for meta-analysis. The relationship between the MELASQoL and MASI scores was found to be mixed. Melasmaarea severity index (MASI) scores within and between tranexamic acid (TA) and hydroquinone (HQ) groups at baseline, and after 4, 8, and 12 weeks A significant decreasing trend was observed in MASI scores at 4, 8, and 12 weeks in both the groups during the study ( P < 0.05). Theefficacy of TXA 2% cream in an emulsion and lotion vehicle for the treatment of melasma was evaluated showing a statistically significant improvement at Week 4 and 8 according to MASI score. 63 A 39 patient double-blind split-face trial study found that application of twice daily TXA 3% cream for 12 weeks was as effective as a solution of Reliabilityassessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method - ScienceDirect. RegisterSign in. View Whileresearchers noted improvements in Hemi- m MASI score after each session, they found greater improvement on the side of the face receiving combination therapy. For example, the average Hemi- m MASI score of patients prior to the first treatment session was 4.04 ± 1.92 on the monotherapy side of the face and 4.11 ± 1.99 Thesecond step involves the calculation of degree of darkness of the identified melasma area as compared to the normal skin. This is done using the Lab colour space [7]. The difference between the Lab values of normal and affected skin will be calculated for each pixel and an average of the darkness of the pixels in areas affected by melasma will be TheMelasma Area and Severity Index (MASI) score, Physician Global Assessment, and pain were measured at baseline and at 4, 8, 12, and 24 weeks. Melasmais defined as an acquired chronic hypermelanosis on sun exposed areas being most frequently found in women with III-V phototypes of Fitzpatrick. The onset average MASI score for the HQ side was 4 (5% CI, 90.9–1.8) and 1.2 (95% IC, 0.8–1.6) after eight weeks (P < 0.001). Inaddition to the MASI scoring of melasma severity, other quantitative measurements have also been designed. 8 The authors’ data showed significant correlation between the average Mexameter (melanin) and MASI scores (p-value=0.004). There was no significant correlation between average Mexameter (erythema), chromameter, and Theseverity of melasma alongside QoL were measured using a melasma area and severity index (MASI) score and melasma quality of life scale (MELASQoL), respectively. The associations among factors and QoL were explored using multivariable methods and stepwise regression analysis. p-values less than 0.05 were considered .
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